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What can be done to prevent graft versus host disease?

Abstract:
Graft versus host disease presents a major obstacle to the widespread application of allogeneic bone marrow transplantation despite improvements in drug prophylaxis. Although animal models are providing an understanding of the biology of the process, opportunities for exploitation of that knowledge for therapeutic purposes are still limited. One way to overcome this impasse is to build on the positive benefits of T-cell purging of marrow, by combining it with intelligent correction of the known negative effects.
Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Journal:
Current opinion in immunology
Volume:
6
Issue:
5
Pages:
777-783
Publication date:
1994-10-05
DOI:
EISSN:
1879-0372
ISSN:
0952-7915
URN:
uuid:dcaccdad-4a76-485b-bf3b-3a9a77e14e47
Source identifiers:
27603
Local pid:
pubs:27603

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