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Journal article

Effect of interferon-α on cortical glutamate in patients with hepatitis C: a proton magnetic resonance spectroscopy study.

Abstract:

BACKGROUND: The development of depressive symptomatology is a recognized complication of treatment with the cytokine interferon-α (IFN-α) and has been seen as supporting inflammatory theories of the pathophysiology of major depression. Major depression has been associated with changes in glutamatergic activity and recent formulations of IFN-induced depression have implicated neurotoxic influences that could also lead to changes in glutamate function. The present study used magnetic resonance ...

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Publication status:
Published

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Publisher copy:
10.1017/s0033291713001062

Authors


Taylor, MJ More by this author
Godlewska, B More by this author
Christmas, D More by this author
Potokar, J More by this author
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Publisher:
Cambridge University Press
Journal:
Psychological medicine
Volume:
44
Issue:
4
Pages:
789-795
Publication date:
2014-03-05
DOI:
EISSN:
1469-8978
ISSN:
0033-2917
URN:
uuid:dc70eb00-1641-427b-8e9f-4457524e6d8c
Source identifiers:
401051
Local pid:
pubs:401051

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