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Journal article

bcl-2 proto-oncogene expression in normal and neoplastic human myeloid cells.

Abstract:

The present study provides immunobiochemical and molecular data on the differentiation-linked expression of the bcl-2 proto-oncogene in normal and neoplastic myeloid cells. Using a recently developed monoclonal antibody (MoAb) to the bcl-2 molecule, staining of normal bone marrow myeloblasts, promyelocytes, and myelocytes, but neither monocytes nor most polymorphonuclear cells, was demonstrated. By two-color flow cytometric analysis, bcl-2 was evidenced in CD33+ and CD33+/CD34+ myeloid cells ...

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Publication status:
Published

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Journal:
Blood
Volume:
79
Issue:
5
Pages:
1291-1298
Publication date:
1992-03-05
EISSN:
1528-0020
ISSN:
0006-4971
URN:
uuid:dad8cfa4-29fc-451a-bc68-4a07a290e5f1
Source identifiers:
486740
Local pid:
pubs:486740

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