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Use of peptide-major histocompatibility complex tetramer technology to study interactions between Staphylococcus aureus proteins and human cells.

Abstract:

In this study, we report the use of peptide-major histocompatibility complex tetramer technology to study the interactions that occur between Staphylococcus aureus proteins and human leukocytes. We demonstrated that this technology can be used to study the activity of superantigens such as toxic shock syndrome toxin 1 and also found that despite similarities to known proteins (i.e., major histocompatibility complex [MHC] class II molecules and superantigens), the S. aureus Eap protein does no...

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Publication status:
Published

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Publisher copy:
10.1128/iai.00875-07

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division, Biomedical Research Centre
Role:
Author
Journal:
Infection and immunity
Volume:
75
Issue:
12
Pages:
5711-5715
Publication date:
2007-12-05
DOI:
EISSN:
1098-5522
ISSN:
0019-9567
URN:
uuid:dad39420-6c9f-409c-a63c-a275f7d5346f
Source identifiers:
21610
Local pid:
pubs:21610

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