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Validated analysis of mortality rates demonstrates distinct genetic mechanisms that influence lifespan.

Abstract:

A key goal of gerontology is to discover the factors that influence the rate of senescence, which in this context refers to the age-dependent acceleration of mortality, inversely related to the morality rate doubling time. In contrast factors that influence only initial mortality rate are thought to be less relevant to the fundamental processes of aging. To resolve these two determinants of mortality rate and lifespan, initial morality rate and rate of senescence are calculated using the Gomp...

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Publication status:
Published

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Publisher copy:
10.1016/j.exger.2008.09.006

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Institution:
University of Oxford
Department:
Oxford, MPLS, Statistics
Role:
Author
Journal:
Experimental gerontology
Volume:
43
Issue:
12
Pages:
1044-1051
Publication date:
2008-12-05
DOI:
EISSN:
1873-6815
ISSN:
0531-5565
URN:
uuid:dab556aa-6ff4-4566-baaa-0589da046bc2
Source identifiers:
97727
Local pid:
pubs:97727

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