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The depletion attraction: an underappreciated force driving cellular organization

Abstract:
Cellular structures are shaped by hydrogen and ionic bonds, plus van der Waals and hydrophobic forces. In cells crowded with macromolecules, a little-known and distinct force - the "depletion attraction" - also acts. We review evidence that this force assists in the assembly of a wide range of cellular structures, ranging from the cytoskeleton to chromatin loops and whole chromosomes.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1083/jcb.200609066

Authors


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Institution:
University of Edinburgh
Department:
School of Physics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Research group:
Nuclear Structure and Function Research Group
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Research group:
Nuclear Structure and Function Research Group
Oxford college:
Lincoln College
Role:
Author



Publisher:
Rockefeller University Press
Journal:
Journal of Cell Biology More from this journal
Volume:
175
Issue:
5
Pages:
681-686
Publication date:
2006-12-01
Edition:
Publisher's version
DOI:
EISSN:
1540-8140
ISSN:
0021-9525


Language:
English
Keywords:
Subjects:
UUID:
uuid:da74b6f2-93a5-42b8-815f-ff5ab8dcb186
Local pid:
ora:1852
Deposit date:
2008-04-22

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