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Recent Biotechnological Applications of Glyco-Nanomaterials

Abstract:
Thanks to the chemically tunable sizes and physical (e.g. electronic, photonic and magnetic) properties, nanomaterials are recently being applied as imaging agents or spectroscopic tools to monitor cellular or biological systems. However, unfunctionalized nanomaterials have a perceived, potential risk of cytotoxicity and a typical lack of cell-specific function. Given the distinct roles of glycans in nature, aqueous solubility/dispersability, biocompatibility, and as endogenous ligands, the properties of nanomaterials can be improved and directed by constructing glycosylated hybrids. In this mini-review, recent developments of glyco-nanomaterials including carbon-based nanomaterials, magnetic nanoparticles, and gold nanoparticles will be discussed. © 2011 American Chemical Society.
Publication status:
Published

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Publisher copy:
10.1021/bk-2011-1091.ch001

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author


Publisher:
American Chemical Society
Host title:
PETITE AND SWEET: GLYCO-NANOTECHNOLOGY AS A BRIDGE TO NEW MEDICINES
Volume:
1091
Pages:
1-13
Publication date:
2011-01-01
DOI:
EISSN:
1947-5918
ISSN:
0097-6156
ISBN:
9780841226883


Pubs id:
pubs:382919
UUID:
uuid:da6e2119-60d6-4962-b057-487f95acaa98
Local pid:
pubs:382919
Source identifiers:
382919
Deposit date:
2013-11-17

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