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Thesis

Investigating novel progenitor cell populations in the fish heart

Abstract:

After cardiac injury, most mammals, including humans, cannot regenerate lost heart muscle with new, functioning cardiomyocytes. The cave-dwelling variant of A mexicanus, a species of teleost fish, is similar to humans and also cannot regenerate. Remarkably, the surface-dwelling variant of the same species can regrow damaged heart muscle, like its fellow teleost fish the zebrafish. Comparison of the surface and cave-dwelling A mexicanus fish is, therefore, a powerful m...

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Abigail Killen-Devine More by this author

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Role:
Supervisor
Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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