Differential adsorption of l- and d-lysine on achiral MFI zeolites as determined by synchrotron x-ray powder diffraction and thermogravimetric analysis

Journal article

Reported here is the first crystallographic observation of stereospecific bindings of l- and d-lysine (Lys) in achiral MFI zeolites. The MFI structure offers inherent geometric and internal confinement effects for the enantiomeric difference in l- and d-Lys adsorption. Notable differences have been observed by circular dichroism (CD) spectroscopy and thermogravimetric analysis (TGA). Distinct l- and d-Lys adsorption behaviours on the H-ZSM-5 framework have been revealed by the Rietveld refinement of high-resolution synchrotron X-ray powder diffraction (SXRD) data and the density-functional theory (DFT) calculations. Despite demonstrating the approach for l- and d-Lys over MFI zeolites at an atomistic resolution, the differential adsorption study sheds light on the rational engineering of molecular interaction(s) with achiral microporous materials for chiral separation purposes.

Authors: Chen, T; Huang, B; Day, S; Tang, C; Tsang, S

• Publication status: Published
• Peer review status: Peer reviewed
• Publisher: Wiley
• Journal: Angewandte Chemie
• Volume: 59
• Issue: 3
• Pages: 1093-1097
• Publication date: 2019-11-08
• DOI: 10.1002/anie.201909352
• EISSN: 1521-3773
• ISSN: 1433-7851
• Pmid: 31701612
• Language: English
• Keywords: circular dichroism; materials science; chirality; FFR; X-ray diffraction; structure elucidation