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Structural studies of orbivirus particles.

Abstract:

We are using crystallographic methods to investigate the structure of AHSV and BTV. Our initial approach was to investigate the structure of the major protein component of the viral core, VP7(T13). This trimeric protein has been studied in several crystal forms from both orbiviruses and reveals a structure made up of conserved domains, capable of conformational changes and possessing a cleavage site. Further crystallographic analyses of native particles have provided a picture of the VP7(T13)...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Structural Biology
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Structural Biology
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Volume:
14
Issue:
SUPPL. 14
Pages:
235-250
Publication date:
1998
ISSN:
0939-1983
URN:
uuid:d9b24c4b-9a96-4a64-b3ee-446978b8b7fb
Source identifiers:
30680
Local pid:
pubs:30680

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