- Abstract:
-
Plant mitochondrial uncoupling protein (UCP) is activated by superoxide suggesting that it may function to minimize mitochondrial reactive oxygen species (ROS) formation. However, the precise mechanism of superoxide activation and the exact function of UCP in plants are not known. We demonstrate that 4-hydroxy-2-nonenal (HNE), a product of lipid peroxidation, and a structurally related compound, trans-retinal, stimulate a proton conductance in potato mitochondria that is inhibitable by GTP (a...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1074/jbc.m408920200
-
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- Journal:
- The Journal of biological chemistry
- Volume:
- 279
- Issue:
- 50
- Pages:
- 51944-51952
- Publication date:
- 2004-12-05
- DOI:
- EISSN:
-
1083-351X
- ISSN:
-
0021-9258
- URN:
-
uuid:d9512071-3d8a-489a-b718-bc5b91d0dbf8
- Source identifiers:
-
32861
- Local pid:
- pubs:32861
- Language:
- English
- Keywords:
- Copyright date:
- 2004
Journal article
Activation and function of mitochondrial uncoupling protein in plants.
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