Journal article
Stable cortical body maps before and after arm amputation
- Abstract:
- The adult brain’s capacity for cortical reorganization remains debated. Using longitudinal neuroimaging in three adults, followed before and up to 5 years after arm amputation, we compared cortical activity elicited by movement of the hand (before amputation) versus phantom hand (after amputation) and lips (before and after amputation). We observed stable cortical representations of both hand and lips in primary sensorimotor regions. By directly quantifying activity changes across amputation, we demonstrate that amputation does not trigger large-scale cortical reorganization.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
-
-
(Preview, Version of record, pdf, 15.1MB, Terms of use)
-
(Supplementary materials, zip, 1.6MB, Terms of use)
-
- Publisher copy:
- 10.1038/s41593-025-02037-7
Authors
- Publisher:
- Nature Research
- Journal:
- Nature Neuroscience More from this journal
- Volume:
- 28
- Issue:
- 10
- Pages:
- 2015-2021
- Publication date:
- 2025-08-21
- Acceptance date:
- 2025-06-27
- DOI:
- EISSN:
-
1546-1726
- ISSN:
-
1097-6256
- Language:
-
English
- Pubs id:
-
2283859
- Local pid:
-
pubs:2283859
- Source identifiers:
-
3346005
- Deposit date:
-
2025-10-06
- ARK identifier:
This ORA record was generated from metadata provided by an external service. It has not been edited by the ORA Team.
Terms of use
- Copyright date:
- 2025
- Licence:
- CC Attribution (CC BY)
If you are the owner of this record, you can report an update to it here: Report update to this record