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Journal article

CD45 variant alleles: possibly increased frequency of a novel exon 4 CD45 polymorphism in HIV seropositive Ugandans.

Abstract:

The CD45 (leucocyte common) antigen is a haemopoietic cell specific tyrosine phosphatase essential for antigen receptor signalling in lymphocytes, and expression of different CD45 isoforms is associated with distinct functions. Here we describe a novel polymorphism in exon 4 (A54G) of the gene encoding CD45 (PTPRC) that results in an amino acid substitution of Thr-19 to Ala in exon 4. The 54G allele was identified in African Ugandan populations and was found with a suggestive but not statisti...

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Publication status:
Published

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Publisher copy:
10.1007/s00251-004-0668-z

Authors


Stanton, T More by this author
Bennett, A More by this author
Kaleebu, P More by this author
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Journal:
Immunogenetics
Volume:
56
Issue:
2
Pages:
107-110
Publication date:
2004-05-05
DOI:
EISSN:
1432-1211
ISSN:
0093-7711
URN:
uuid:d8b179cc-e5b4-4f23-9778-ba931caf07bf
Source identifiers:
32667
Local pid:
pubs:32667

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