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Journal article

Co-evolution of human immunodeficiency virus and cytotoxic T-lymphocyte responses.

Abstract:

After more than a decade of intensive research, the precise role of human immunodeficiency virus (HIV)-specific cytotoxic T lymphocytes (CTL) in determining the course of the infection remains open to argument. It is established that HIV-specific CTL appear early in the infection and are temporally associated with the clearance of culturable virus from the blood; that CTL are generally detectable at very high levels throughout the asymptomatic phase and decline at the time of progression to A...

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Publication status:
Published

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Authors


Goulder, P More by this author
Rowland-Jones, S More by this author
Phillips, R More by this author
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Journal:
Immunological reviews
Volume:
159
Issue:
1
Pages:
17-29
Publication date:
1997-10-05
DOI:
EISSN:
1600-065X
ISSN:
0105-2896
URN:
uuid:d8aa794e-0854-4cf0-8b40-901b1b7237f3
Source identifiers:
176659
Local pid:
pubs:176659

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