Functional connectomics from resting-state fMRI

Journal article

Spontaneous fluctuations in activity in different parts of the brain can be used to study functional brain networks. We review the use of resting-state functional MRI (rfMRI) for the purpose of mapping the macroscopic functional connectome. After describing MRI acquisition and image-processing methods commonly used to generate data in a form amenable to connectomics network analysis, we discuss different approaches for estimating network structure from that data. Finally, we describe new possibilities resulting from the high-quality rfMRI data being generated by the Human Connectome Project and highlight some upcoming challenges in functional connectomics. © 2013 Elsevier Ltd.

Authors: Smith, S; Vidaurre, D; Beckmann, C; Beckmann, C; Beckmann, C

• Journal: Trends in Cognitive Sciences
• Volume: 17
• Issue: 12
• Pages: 666-682
• Publication date: 2013-12-01
• DOI: 10.1016/j.tics.2013.09.016
• EISSN: 1879-307X
• ISSN: 1364-6613