Routine versus clinically driven laboratory monitoring and first-line antiretroviral therapy strategies in African children with HIV (ARROW): a 5-year open-label randomised factorial trial.

Kekitiinwa, A; Cook, A; Nathoo, K; Mugyenyi, P; Nahirya-Ntege, P; Bakeera-Kitaka, S; Thomason, M; Bwakura-Dangarembizi, M; Musiime, V; Munderi, P; Naidoo-James, B; Vhembo, T; Tumusiime, C; Katuramu, R; Crawley, J; Prendergast, AJ; Musoke, P; Walker, AS; Gibb, DM

Abstract:

BACKGROUND: No trials have investigated routine laboratory monitoring for children with HIV, nor four-drug induction strategies to increase durability of first-line antiretroviral therapy (ART). METHODS: In this open-label parallel-group trial, Ugandan and Zimbabwean children or adolescents with HIV, aged 3 months to 17 years and eligible for ART, were randomly assigned in a factorial design. Randomisation was to either clinically driven monitoring or routine laboratory and clinical monitorin...

Expand abstract

Actions

Email

Email this record

Send the bibliographic details of this record to your email address.

Your Email
Please enter the email address that the record information will be sent to.

-
Your message (optional)
Please add any additional information to be included within the email.
Cite

Cite this record

APA Style

Kekitiinwa, A., Cook, A., Nathoo, K., Mugyenyi, P., Nahirya-Ntege, P., Bakeera-Kitaka, S., Thomason, M., Bwakura-Dangarembizi, M., Musiime, V., Munderi, P., Naidoo-James, B., Vhembo, T., Tumusiime, C., Katuramu, R., Crawley, J., Prendergast, A. J., Musoke, P., Walker, A. S., & Gibb, D. M. (2013). Routine versus clinically driven laboratory monitoring and first-line antiretroviral therapy strategies in African children with HIV (ARROW): a 5-year open-label randomised factorial trial. Lancet, 381(9875), 1391–1403.

MLA Style

Kekitiinwa, A., et al. “Routine versus Clinically Driven Laboratory Monitoring and First-Line Antiretroviral Therapy Strategies in African Children with HIV (ARROW): a 5-Year Open-Label Randomised Factorial Trial.” Lancet, vol. 381, no. 9875, 2013, pp. 1391–403.

Chicago Style

Kekitiinwa, A, A Cook, K Nathoo, P Mugyenyi, P Nahirya-Ntege, S Bakeera-Kitaka, M Thomason, et al. 2013. “Routine versus Clinically Driven Laboratory Monitoring and First-Line Antiretroviral Therapy Strategies in African Children with HIV (ARROW): a 5-Year Open-Label Randomised Factorial Trial.” Lancet 381 (9875): 1391–1403.
Tweet
Print