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Journal article

Genome-wide association studies: potential next steps on a genetic journey.

Abstract:

Genome-wide association studies have successfully identified numerous loci at which common variants influence disease risk or quantitative traits. Despite these successes, the variants identified by these studies have generally explained only a small fraction of the heritable component of disease risk, and have not pinpointed with certainty the causal variant(s) at the associated loci. Furthermore, the mechanisms of action by which associated loci influence disease or quantitative phenotypes ...

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Publication status:
Published

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Publisher copy:
10.1093/hmg/ddn289

Authors


McCarthy, MI More by this author
Hirschhorn, JN More by this author
Journal:
Human molecular genetics
Volume:
17
Issue:
R2
Pages:
R156-R165
Publication date:
2008-10-05
DOI:
EISSN:
1460-2083
ISSN:
0964-6906
URN:
uuid:d80f5926-b588-4853-8a3f-6ff61712a05d
Source identifiers:
29632
Local pid:
pubs:29632

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