Journal article icon

Journal article

A silyl sulfinylamine reagent enables the modular synthesis of sulfonimidamides via primary sulfinamides

Abstract:

A new N-silyl sulfinylamine reagent allows the rapid preparation of a broad range of (hetero)aryl, alkenyl, and alkyl primary sulfinamides, using Grignard, organolithium, or organozinc reagents to introduce the carbon fragment. Treatment of these primary sulfinamides with an amine in the presence of a hypervalent iodine reagent leads directly to NH-sulfonimidamides. This two-step sequence is straightforward to perform and provides a modular approach to sulfonimidamides, allowing ready variati...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1021/acs.orglett.2c00347

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Oxford college:
Lincoln College
Role:
Author
ORCID:
0000-0002-0636-6471
Publisher:
American Chemical Society
Journal:
Organic Letters More from this journal
Volume:
24
Issue:
8
Pages:
1711-1715
Publication date:
2022-02-21
Acceptance date:
2022-02-21
DOI:
EISSN:
1523-7052
ISSN:
1523-7060
Pmid:
35188396
Language:
English
Keywords:
Pubs id:
1241038
Local pid:
pubs:1241038
Deposit date:
2022-02-25

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP