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A full genome screen for autism with evidence for linkage to a region on chromosome 7q. International Molecular Genetic Study of Autism Consortium.

Abstract:

Autism is characterized by impairments in reciprocal social interaction and communication, and restricted and sterotyped patterns of interests and activities. Developmental difficulties are apparent before 3 years of age and there is evidence for strong genetic influences most likely involving more than one susceptibility gene. A two-stage genome search for susceptibility loci in autism was performed on 87 affected sib pairs plus 12 non-sib affected relative-pairs, from a total of 99 families...

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Publisher copy:
10.1093/hmg/7.3.571

Authors


Matthews, N More by this author
Palferman, S More by this author
Wallace, S More by this author
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Journal:
Human molecular genetics
Volume:
7
Issue:
3
Pages:
571-578
Publication date:
1998-03-05
DOI:
EISSN:
1460-2083
ISSN:
0964-6906
URN:
uuid:d66f0c7c-0edc-4822-a65b-148aa6136af7
Source identifiers:
94577
Local pid:
pubs:94577

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