Delineation of early attentional control difficulties in fragile X syndrome: focus on neurocomputational changes.

Journal article

Fragile X syndrome (FXS) is due to the silencing of a single X-linked gene and it is associated with striking attentional difficulties. As FXS is well characterised at the cellular level, the condition provides a unique opportunity to investigate how a genetic dysfunction can impact on the development of neurocomputational properties relevant to attention. Thirteen young boys with FXS and 13 mental-age-matched typically developing controls performed a touch-screen-based search task that manip...

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Authors: Scerif, G; Cornish, K; Wilding, J; Driver, J; Karmiloff-Smith, A

• Publication status: Published
• Journal: Neuropsychologia
• Volume: 45
• Issue: 8
• Pages: 1889-1898
• Publication date: 2007-04-01
• DOI: 10.1016/j.neuropsychologia.2006.12.005
• EISSN: 1873-3514
• ISSN: 0028-3932
• Language: English
• Keywords: Child, Preschool; Attention; Case-Control Studies; Neuropsychological Tests; Psychomotor Performance; Fragile X Syndrome; Humans; Computer-Aided Design; Reaction Time; Male