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Journal article

The immunophenotype of osteoclasts and macrophage polykaryons.

Abstract:

AIM: Osteoclasts are multinucleated cells which are specialised to carry out lacunar bone resorption. Osteoclasts form part of the mononuclear phagocyte system, and immunophenotypic criteria for distinction from macrophage polykaryons include expression of CD51 (vitronectin receptor) and absence of HLA-DR and CD14. METHODS: The expression of CD14, CD163, HLA-DR and CD51 in formalin-fixed paraffin-embedded sections of normal bone and neoplastic and non-neoplastic lesions of bone and soft tiss...

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Publication status:
Published

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Publisher copy:
10.1136/jcp.2011.090852

Authors


Maggiani, F More by this author
Forsyth, R More by this author
Hogendoorn, PC More by this author
Krenacs, T More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Journal:
Journal of clinical pathology
Volume:
64
Issue:
8
Pages:
701-705
Publication date:
2011-08-05
DOI:
EISSN:
1472-4146
ISSN:
0021-9746
URN:
uuid:d55d01fd-afe7-46fb-8b44-1e4ff5aec006
Source identifiers:
138861
Local pid:
pubs:138861

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