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Tenascin-C at a glance

Abstract:

Tenascin-C (TNC) is a hexameric, multimodular extracellular matrix protein with several molecular forms that are created through alternative splicing and protein modifications. It is highly conserved amongst vertebrates, and molecular phylogeny indicates that it evolved before fibronectin. Tenascin-C has many extracellular binding partners, including matrix components, soluble factors and pathogens; it also influences cell phenotype directly through interactions with cell surface receptors. T...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1242/jcs.190546

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS, KIR
Role:
Author
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Funding agency for:
Midwood, K
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Funding agency for:
Midwood, K
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Funding agency for:
Midwood, K
Publisher:
Company of Biologists Publisher's website
Journal:
Journal of Cell Science Journal website
Volume:
129
Issue:
23
Pages:
4321-4327
Publication date:
2016-12-01
Acceptance date:
2016-11-10
DOI:
EISSN:
1477-9137
ISSN:
0021-9533
Pubs id:
pubs:664285
URN:
uri:d54b1a2f-bce4-4196-b8a3-4983804eb5f3
UUID:
uuid:d54b1a2f-bce4-4196-b8a3-4983804eb5f3
Local pid:
pubs:664285
Paper number:
23

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