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Psychobiotics and the Manipulation of Bacteria-Gut-Brain Signals.

Abstract:

Psychobiotics were previously defined as live bacteria (probiotics) which, when ingested, confer mental health benefits through interactions with commensal gut bacteria. We expand this definition to encompass prebiotics, which enhance the growth of beneficial gut bacteria. We review probiotic and prebiotic effects on emotional, cognitive, systemic, and neural variables relevant to health and disease. We discuss gut-brain signalling mechanisms enabling psychobiotic effects, such as metabolite ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1016/j.tins.2016.09.002

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Department:
Oxford, MSD, Experimental Psychology
Role:
Author
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Department:
Oxford, MSD, Experimental Psychology
Role:
Author
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Grant:
HRA_POR/2011/23; HRA_POR/2012/32, HRAPOR-2-14-647
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Grant:
MYNEWGUT FP7-KBBE-2013-7
Publisher:
Elsevier (Cell Press) Publisher's website
Journal:
Trends in Neurosciences Journal website
Volume:
39
Issue:
11
Pages:
763-781
Publication date:
2016-10-25
Acceptance date:
2016-01-01
DOI:
EISSN:
1878-108X
ISSN:
0166-2236
Pubs id:
pubs:656783
URN:
uri:d4f6a6b0-902d-44fa-90cb-93fe87aab949
UUID:
uuid:d4f6a6b0-902d-44fa-90cb-93fe87aab949
Local pid:
pubs:656783
Paper number:
11

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