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Neurobiological mechanisms underlying the blocking effect in aversive learning.

Abstract:

Current theories of classical conditioning assume that learning depends on the predictive relationship between events, not just on their temporal contiguity. Here we employ the classic experiment substantiating this reasoning-the blocking paradigm-in combination with functional magnetic resonance imaging (fMRI) to investigate whether human amygdala responses in aversive learning conform to these assumptions. In accordance with blocking, we demonstrate that significantly stronger behavioral an...

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Büchel, C More by this author
Journal:
The Journal of neuroscience : the official journal of the Society for Neuroscience
Volume:
32
Issue:
38
Pages:
13164-13176
Publication date:
2012-09-05
DOI:
EISSN:
1529-2401
ISSN:
0270-6474
URN:
uuid:d4d71f6b-1d2b-4d89-b79b-8ea91bcbc557
Source identifiers:
352530
Local pid:
pubs:352530

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