Kynurenine pathway metabolites in Alzheimer's disease.
Metabolites of tryptophan, produced via the kynurenine pathway (kynurenines) have been linked to Alzheimer’s disease (AD) in small cohorts with conflicting results.
To compare differences in plasma kynurenine levels between AD and controls and identify potential associations with cognition.
The study included 65 histopathologically-confirmed AD patients and 65 cognitively-screened controls from the Oxford Project to In...Expand abstract
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- Peer reviewed
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- IOS Press and the authors
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- © 2017 - IOS Press and the authors. All rights reserved. The final publication is available at IOS Press through http://dx.doi.org/10.3233/jad-170485