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Journal article

Kynurenine pathway metabolites in Alzheimer's disease.

Abstract:

Background

Metabolites of tryptophan, produced via the kynurenine pathway (kynurenines) have been linked to Alzheimer’s disease (AD) in small cohorts with conflicting results.

Objective

To compare differences in plasma kynurenine levels between AD and controls and identify potential associations with cognition.

Methods

The study included 65 histopathologically-confirmed AD patients and 65 cognitively-screened controls from the Oxford Project to In...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Files:
Publisher copy:
10.3233/jad-170485

Authors


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Role:
Author
ORCID:
0000-0003-3520-7530
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Pharmacology
Role:
Author
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Bristol-Myers Squibb More from this funder
Medical Research Council More from this funder
Charles Wolfson Charitable Trust More from this funder
Publisher:
IOS Press Publisher's website
Journal:
Journal of Alzheimer's Disease Journal website
Volume:
60
Issue:
2
Pages:
495-504
Publication date:
2017-09-05
Acceptance date:
2017-07-07
DOI:
EISSN:
1875-8908
ISSN:
1387-2877
Pubs id:
pubs:725881
URN:
uri:d4714fac-9c39-484a-baf9-82dd68dc1984
UUID:
uuid:d4714fac-9c39-484a-baf9-82dd68dc1984
Local pid:
pubs:725881

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