- Abstract:
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AbstractTermination of RNA polymerase II (Pol II) transcription is an important step in the transcription cycle, which involves the dislodgement of polymerase from DNA, leading to release of a functional transcript. Recent studies have identified the key players required for this process and showed that a common feature of these proteins is a conserved domain that interacts with the phosphorylated C-terminus of Pol II (CTD-interacting domain, CID). However, the mechanism by which transcriptio...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
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(pdf, 2.5MB)
-
- Publisher copy:
- 10.1038/ncomms14861
-
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- Publisher:
- Nature Publishing Group Publisher's website
- Journal:
- Nature Communications Journal website
- Volume:
- 8
- Issue:
- 1
- Pages:
- 14861
- Acceptance date:
- 2016-04-03
- DOI:
- EISSN:
-
2041-1723
- Pubs id:
-
pubs:667829
- URN:
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uri:d4433d0f-d17c-4df6-8691-f1ce25ed1a97
- UUID:
-
uuid:d4433d0f-d17c-4df6-8691-f1ce25ed1a97
- Local pid:
- pubs:667829
- Paper number:
- 1
- Keywords:
- Copyright holder:
- Wittmann et al.
- Notes:
- © The Author(s) 2017. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
Journal article
The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA
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