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Evaluation of a PfHRP2 and a pLDH-based rapid diagnostic test for the diagnosis of severe malaria in 2 populations of African children.

Abstract:

BACKGROUND: Rapid diagnostic tests (RDTs) now play an important role in the diagnosis of falciparum malaria in many countries where the disease is endemic. Although these tests have been extensively evaluated in uncomplicated falciparum malaria, reliable data on their performance for diagnosing potentially lethal severe malaria is lacking. METHODS: We compared a Plasmodium falciparum histidine-rich-protein2 (PfHRP₂)-based RDT and a Plasmodium lactate dehydrogenase (pLDH)-based RDT with routin...

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Publication status:
Published

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Publisher copy:
10.1093/cid/cir143

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Journal:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Volume:
52
Issue:
9
Pages:
1100-1107
Publication date:
2011-05-05
DOI:
EISSN:
1537-6591
ISSN:
1058-4838
URN:
uuid:d44121b0-0dbf-4318-a667-3b8453a02d77
Source identifiers:
131357
Local pid:
pubs:131357

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