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Systematic dose-extension of octreotide LAR: the importance of individual tailoring of treatment in patients with acromegaly.

Abstract:

OBJECTIVE: The depot long-acting somatostatin analogue octreotide LAR (LAR) provides effective and well-tolerated treatment for acromegaly. Despite a 4-weekly recommended injection frequency, prolonged duration of GH suppression has been observed in some patients following treatment with long-acting somatostatin analogues. The aim of our study was to perform a prospective systematic study to determine whether extending the interval between doses of LAR allows maintenance of 'safe' GH in sele...

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Journal:
Clinical endocrinology More from this journal
Volume:
61
Issue:
2
Pages:
224-231
Publication date:
2004-08-01
DOI:
EISSN:
1365-2265
ISSN:
0300-0664
Language:
English
Keywords:
Pubs id:
pubs:10704
UUID:
uuid:d43ee285-bfc3-428e-a4b3-577b32ad5274
Local pid:
pubs:10704
Source identifiers:
10704
Deposit date:
2012-12-19

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