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The IDEAL framework for machine perfusion in liver transplantation

Abstract:
Liver transplantation is challenged by organ scarcity and ageing donors. Machine perfusion is a promising technique to enhance organ preservation and assessment, improving liver utilization and patient outcomes. Here, we discuss current practices in machine perfusion using the IDEAL framework and outline the steps needed to advance this technology clinically.
Publication status:
Published
Peer review status:
Reviewed (other)

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Files:
Publisher copy:
10.1038/s41575-025-01085-5

Authors

More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Surgical Sciences
Oxford college:
Green Templeton College
Role:
Author
ORCID:
0000-0003-0841-9685

Contributors

Role:
Contributor
Institution:
University of Oxford
Division:
MSD
Department:
Surgical Sciences
Role:
Contributor
ORCID:
0000-0003-3846-0101


Publisher:
Springer Nature
Journal:
Nature Reviews Gastroenterology and Hepatology More from this journal
Volume:
22
Issue:
10
Pages:
669–671
Place of publication:
England
Publication date:
2025-06-16
Acceptance date:
2025-05-23
DOI:
EISSN:
1759-5053
ISSN:
1759-5045
Pmid:
40523963


Language:
English
Subtype:
Comment
Pubs id:
2132614
Local pid:
pubs:2132614
Deposit date:
2025-10-01
ARK identifier:

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