- Abstract:
-
BACKGROUND: There is increasing recognition of antibody-mediated immunotherapy-responsive neurologic diseases and a need for appropriate immunoassays. OBJECTIVES: To develop a clinically applicable quantitative assay to detect the presence of aquaporin-4 (AQP4) antibodies in patients with neuromyelitis optica and to characterize the anti-AQP4 antibodies. DESIGN: We compared a simple new quantitative fluorescence immunoprecipitation assay (FIPA) with both indirect immunofluorescence and an AQP...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1001/archneur.65.7.913
-
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- Journal:
- Archives of neurology
- Volume:
- 65
- Issue:
- 7
- Pages:
- 913-919
- Publication date:
- 2008-07-05
- DOI:
- EISSN:
-
1538-3687
- ISSN:
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0003-9942
- URN:
-
uuid:d3a987e1-f18b-4a56-826f-1cfe49da234c
- Source identifiers:
-
240893
- Local pid:
- pubs:240893
- Copyright date:
- 2008
Journal article
Aquaporin-4 antibodies in neuromyelitis optica and longitudinally extensive transverse myelitis.
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