Journal article
Methodological guidelines to study extracellular vesicles
- Abstract:
- Owing to the relationship between extracellular vesicles (EVs) and physiological and pathological conditions, the interest in EVs is exponentially growing. EVs hold high hopes for novel diagnostic and translational discoveries. This review provides an expert-based update of recent advances in the methods to study EVs and summarizes currently accepted considerations and recommendations from sample collection to isolation, detection, and characterization of EVs. Common misconceptions and methodological pitfalls are highlighted. Although EVs are found in all body fluids, in this review, we will focus on EVs from human blood, not only our most complex but also the most interesting body fluid for cardiovascular research.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
-
-
(Preview, Accepted manuscript, pdf, 7.2MB, Terms of use)
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- Publisher copy:
- 10.1161/CIRCRESAHA.117.309417
Authors
- Publisher:
- American Heart Association
- Journal:
- Circulation Research More from this journal
- Volume:
- 120
- Issue:
- 10
- Pages:
- 1632-1648
- Publication date:
- 2017-05-11
- Acceptance date:
- 2017-04-13
- DOI:
- ISSN:
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0009-7330, 1524-4571
- Language:
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English
- Keywords:
- Pubs id:
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pubs:695830
- UUID:
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uuid:d3840ad6-9815-4cea-9f5c-b48ae9ce6388
- Local pid:
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pubs:695830
- Source identifiers:
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695830
- Deposit date:
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2017-05-29
- ARK identifier:
Terms of use
- Copyright holder:
- American Heart Association, Inc
- Copyright date:
- 2017
- Notes:
- Copyright 2017 American Heart Association, Inc. This is the author accepted manuscript following peer review version of the article. The final version is available online from American Heart Association at: https://doi.org/10.1161/CIRCRESAHA.117.309417
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