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Genome-wide association studies in mice.

Abstract:

Genome-wide association studies (GWASs) have transformed the field of human genetics and have led to the discovery of hundreds of genes that are implicated in human disease. The technological advances that drove this revolution are now poised to transform genetic studies in model organisms, including mice. However, the design of GWASs in mouse strains is fundamentally different from the design of human GWASs, creating new challenges and opportunities. This Review gives an overview of the nove...

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Publication status:
Published

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Publisher copy:
10.1038/nrg3335

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Journal:
Nature reviews. Genetics
Volume:
13
Issue:
11
Pages:
807-817
Publication date:
2012-11-05
DOI:
EISSN:
1471-0064
ISSN:
1471-0056
URN:
uuid:d34c55d1-cec5-4519-96dc-237b14aed17f
Source identifiers:
353954
Local pid:
pubs:353954

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