Journal article icon

Journal article

Regulation of hepcidin by erythropoiesis: The story so far.

Abstract:

Hepcidin is the master regulator of systemic iron homeostasis, facilitating iron balance by controlling intestinal iron absorption and recycling. Hepcidin levels are suppressed when erythropoiesis is stimulated, for example following acute blood loss, appropriately enhancing cellular iron export to the plasma to support production of new red blood cells. However, persistent increased and ineffective erythropoiesis, for example in thalassemia, results in sustained elevations in iron absorption...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM - Investigative Medicine Division
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Jenner Institute
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM - Investigative Medicine Division
Role:
Author
More from this funder
Name:
Pfizer Rare Diseases Consortium
More from this funder
Name:
National Institute for Health Research
More from this funder
Name:
Cooley’s Anemia Foundation
More from this funder
Name:
Bill and Melinda Gates Foundation
Publisher:
Annual Reviews
Journal:
Annual Review of Nutrition More from this journal
Volume:
36
Issue:
1
Pages:
417-434
Publication date:
2016-05-04
DOI:
EISSN:
1545-4312
ISSN:
0199-9885
Pmid:
27146013
Language:
English
Keywords:
Pubs id:
pubs:619921
UUID:
uuid:d3389616-f4a9-4644-9344-c83afea70098
Local pid:
pubs:619921
Source identifiers:
619921
Deposit date:
2017-07-04

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP