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Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinoma.

Abstract:

Hepatocellular carcinoma (HCC) is a highly heterogeneous disease, and prior attempts to develop genomic-based classification for HCC have yielded highly divergent results, indicating difficulty in identifying unified molecular anatomy. We performed a meta-analysis of gene expression profiles in data sets from eight independent patient cohorts across the world. In addition, aiming to establish the real world applicability of a classification system, we profiled 118 formalin-fixed, paraffin-emb...

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Oxford Ludwig Institute
Role:
Author
Journal:
Cancer research More from this journal
Volume:
69
Issue:
18
Pages:
7385-7392
Publication date:
2009-09-01
DOI:
EISSN:
1538-7445
ISSN:
0008-5472
Language:
English
Keywords:
Pubs id:
pubs:489969
UUID:
uuid:d32f13da-9bda-42d2-999b-dfbdb5e4c680
Local pid:
pubs:489969
Source identifiers:
489969
Deposit date:
2014-11-22

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