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Experimentally revised repertoire of putative contingency loci in Neisseria meningitidis strain MC58: evidence for a novel mechanism of phase variation.

Abstract:

Analysis of the genome sequence of Neisseria meningitidis strain MC58 revealed 65 genes associated with simple sequence repeats. Experimental evidence of phase variation exists for only 14 of these 65 putatively phase variable genes. We investigated the phase variable potential of the remaining 51 genes. The repeat tract associated with 20 of these 51 genes was sequenced in 26 genetically distinct strains. This analysis provided circumstantial evidence for or against the phase variability of ...

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Publication status:
Published

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Authors


van de Ven, T More by this author
Mouchel, N More by this author
Jeffries, AC More by this author
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Journal:
Molecular microbiology
Volume:
50
Issue:
1
Pages:
245-257
Publication date:
2003-10-05
DOI:
EISSN:
1365-2958
ISSN:
0950-382X
URN:
uuid:d2fb542e-f004-479b-b022-9bb22bb9f45f
Source identifiers:
115611
Local pid:
pubs:115611

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