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Feasibility of wearable monitors to detect heart rate variability in children with hand, foot and mouth disease

Abstract:
Hand foot and mouth disease (HFMD) is caused by a variety of enteroviruses, and occurs in large outbreaks in which a small proportion of children deteriorate rapidly with cardiopulmonary failure. Determining which children are likely to deteriorate is difficult and health systems may become overloaded during outbreaks as many children require hospitalization for monitoring. Heart rate variability (HRV) may help distinguish those with more severe diseases but requires simple scalable methods to collect ECG data.We carried out a prospective observational study to examine the feasibility of using wearable devices to measure HRV in 142 children admitted with HFMD at a children's hospital in Vietnam. ECG data were collected in all children. HRV indices calculated were lower in those with enterovirus A71 associated HFMD compared to those with other viral pathogens.HRV analysis collected from wearable devices is feasible in a low and middle income country (LMIC) and may help classify disease severity in HFMD.
Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1186/s12879-024-08994-x

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Publisher:
BioMed Central
Journal:
BMC Infectious Diseases More from this journal
Volume:
24
Issue:
1
Article number:
205
Place of publication:
England
Publication date:
2024-02-15
Acceptance date:
2024-01-08
DOI:
ISSN:
1471-2334
Pmid:
38360603


Language:
English
Keywords:
Pubs id:
1620295
Local pid:
pubs:1620295
Deposit date:
2024-03-18

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