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Journal article : Review

The utility of animal models to inform the next generation of human space exploration

Abstract:
Animals have played a vital role in every stage of space exploration, from early sub-orbital flights to contemporary missions. New physiological and psychological challenges arise with plans to venture deeper into the solar system. Advances in chimeric and knockout animal models, along with genetic modification techniques have enhanced our ability to study the effects of microgravity in greater detail. However, increased investment in the purposeful design of habitats and payloads, as well as in AI-enhanced behavioral monitoring in orbit can better support the ethical and effective use of animals in deep space research.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/s41526-025-00460-5

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Biology
Sub department:
Biology
Role:
Author
ORCID:
0000-0003-2454-1592


Publisher:
Nature Research
Journal:
npj Microgravity More from this journal
Volume:
11
Issue:
1
Article number:
7
Publication date:
2025-02-22
Acceptance date:
2025-02-10
DOI:
EISSN:
2373-8065
ISSN:
2373-8065


Language:
English
Subtype:
Review
Source identifiers:
2708121
Deposit date:
2025-02-22
This ORA record was generated from metadata provided by an external service. It has not been edited by the ORA Team.

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