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O-h what a surprise

Abstract:

Only two trypanosome subspecies are able to cause human African trypanosomiasis. To establish an infection in human blood, they must overcome the innate immune system by resisting the toxic effects of trypanolytic factor 1 and trypanolytic factor 2. These lipoprotein complexes contain an active, pore-forming component, apolipoprotein L1 (ApoL1), that causes trypanosome cell death3. One of the two humaninfective subspecies, Trypanosoma brucei rhodesiense, differs from non-infective trypanosome...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1038/s41564-018-0211-x

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Biochemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Chemistry
Subgroup:
Physical and Theoretical Chemistry Laboratory
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Chemistry
Subgroup:
Physical and Theoretical Chemistry Laboratory
Role:
Author
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Publisher:
Nature Publishing Group Publisher's website
Journal:
Nature Microbiology Journal website
Volume:
3
Issue:
8
Pages:
856-857
Publication date:
2018-07-25
Acceptance date:
2018-07-25
DOI:
EISSN:
2058-5276
Pubs id:
pubs:905128
URN:
uri:d2aaee13-cf68-4f31-a14b-2a25ca758fe2
UUID:
uuid:d2aaee13-cf68-4f31-a14b-2a25ca758fe2
Local pid:
pubs:905128
Language:
English
Keywords:

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