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Enantioselective one-pot synthesis of dihydroquinolones via BINOL-derived Lewis acid catalysis

Abstract:

A high-yielding and diastereoselective route to biologically significant 2-aryl- and 2-alkyl-3-amido dihydroquinolones has been developed in up to 90 : 10 e.r. by employing a novel Lewis acidic BINOL-derived copper(II) catalyst.

Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1039/c4ob00627e

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author
ORCID:
0000-0001-9728-2339
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Oxford college:
University College
Role:
Author
ORCID:
0000-0002-8849-488X
Publisher:
Royal Society of Chemistry
Journal:
Organic and Biomolecular Chemistry More from this journal
Volume:
12
Issue:
28
Pages:
5094-5097
Publication date:
2014-06-13
Acceptance date:
2014-06-03
DOI:
EISSN:
1477-0539
ISSN:
1477-0520
Pmid:
24927823
Language:
English
Keywords:
Pubs id:
pubs:469511
UUID:
uuid:d2764cf3-0736-4654-8d49-185dbbcf5da6
Local pid:
pubs:469511
Source identifiers:
469511
Deposit date:
2018-03-27

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