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A gene regulatory network orchestrates neural crest formation.

Abstract:

The neural crest is a multipotent, migratory cell population that is unique to vertebrate embryos and gives rise to many derivatives, ranging from the peripheral nervous system to the craniofacial skeleton and pigment cells. A multimodule gene regulatory network mediates the complex process of neural crest formation, which involves the early induction and maintenance of the precursor pool, emigration of the neural crest progenitors from the neural tube via an epithelial to mesenchymal transit...

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Publisher copy:
10.1038/nrm2428

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
Weatherall Insti. of Molecular Medicine
Role:
Author
Journal:
Nature reviews. Molecular cell biology
Volume:
9
Issue:
7
Pages:
557-568
Publication date:
2008-07-01
DOI:
EISSN:
1471-0080
ISSN:
1471-0072
Source identifiers:
264312
Language:
English
Keywords:
Pubs id:
pubs:264312
UUID:
uuid:d2718b2e-85c9-4948-9aca-3cf5feac43c5
Local pid:
pubs:264312
Deposit date:
2012-12-19

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