Journal article

Falciparum malaria mortality in sub-Saharan Africa in the pretreatment era

Abstract:: Driven by the malaria-protective effect of sickle-cell trait, balancing selection results in hemoglobin S equilibrium allele frequencies of between 15% and 20% in areas of high Plasmodium falciparum transmission in sub-Saharan Africa. From this we estimate that the malaria-attributable childhood mortality in the pretreatment era was between 15% and 24%.

Publication status:: Published

Peer review status:: Peer reviewed

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APA Style

Watson, J. A., White, N. J., & Dondorp, A. M. (2021). Falciparum malaria mortality in sub-Saharan Africa in the pretreatment era. Trends in Parasitology, 38(1), 11–14.

MLA Style

Watson, JA, et al. “Falciparum Malaria Mortality in Sub-Saharan Africa in the Pretreatment Era.” Trends in Parasitology, vol. 38, no. 1, 2021, pp. 11–14.

Chicago Style

Watson, JA, NJ White, and AM Dondorp. 2021. “Falciparum Malaria Mortality in Sub-Saharan Africa in the Pretreatment Era.” Trends in Parasitology 38 (1): 11–14.
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Publisher copy:: 10.1016/j.pt.2021.10.005

Authors

+ Watson, JA More by this author

Institution:: University of Oxford
Division:: MSD
Department:: NDM
Sub department:: Tropical Medicine
Sub unit:: MORU Mahidol Oxford Tropical Medicine Research Unit
Role:: Author
ORCID:: 0000-0001-5524-0325

+ White, NJ More by this author

Institution:: University of Oxford
Division:: MSD
Department:: NDM
Sub department:: Tropical Medicine
Sub unit:: MORU Mahidol Oxford Tropical Medicine Research Unit
Role:: Author
ORCID:: 0000-0002-1897-1978

+ Dondorp, AM More by this author

Institution:: University of Oxford
Division:: MSD
Department:: NDM
Sub department:: Tropical Medicine
Sub unit:: MORU Mahidol Oxford Tropical Medicine Research Unit
Role:: Author
ORCID:: 0000-0001-5190-2395

+ Wellcome Trust More from this funder

Grant:: 093956/Z/10/Z; 220211/A/20/A; 223253/Z/21/Z

Publisher:: Cell Press
Journal:: Trends in Parasitology More from this journal
Volume:: 38
Issue:: 1
Pages:: 11-14
Place of publication:: England
Publication date:: 2021-11-30
Acceptance date:: 2021-10-25
DOI:: 10.1016/j.pt.2021.10.005
EISSN:: 1471-5007
ISSN:: 1471-4922
Pmid:: 34862145

Language:: English
Keywords:: malaria-attributable mortality

sickle cell

hemoglobin S

falciparum malaria
Pubs id:: 1223372
Local pid:: pubs:1223372
Deposit date:: 2023-11-23
ARK identifier:: ark:/29072/ora_d26e3a7d79b3427dbc7e38866e8a9e1e

Terms of use

Copyright holder:: Elsevier
Copyright date:: 2021
Rights statement:: © 2021 Elsevier Ltd. All rights reserved.

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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