Fast assessment of stroke and transient ischaemic attack to prevent early recurrence (FASTER): a randomised controlled pilot trial.

Journal article

BACKGROUND: Patients with transient ischaemic attack (TIA) or minor stroke are at high immediate risk of stroke. The optimum early treatment options for these patients are not known. METHODS: Within 24 h of symptom onset, we randomly assigned, in a factorial design, 392 patients with TIA or minor stroke to clopidogrel (300 mg loading dose then 75 mg daily; 198 patients) or placebo (194 patients), and simvastatin (40 mg daily; 199 patients) or placebo (193 patients). All patients were also giv...

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Authors: Kennedy, J; Hill, MD; Ryckborst, K; Eliasziw, M; Demchuk, A

• Publication status: Published
• Journal: Lancet. Neurology
• Volume: 6
• Issue: 11
• Pages: 961-969
• Publication date: 2007-11-01
• DOI: 10.1016/s1474-4422(07)70250-8
• EISSN: 1474-4465
• ISSN: 1474-4422
• Language: English
• Keywords: Humans; Platelet Aggregation Inhibitors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Risk Reduction Behavior; FASTER Investigators; Drug Therapy, Combination; Stroke; Aspirin; Male; Ticlopidine; Time Factors; Aged; Incidence; Severity of Illness Index; Ischemic Attack, Transient; Simvastatin; Recurrence; Middle Aged; Treatment Outcome; Female; Pilot Projects; Aged, 80 and over; Cerebral Hemorrhage