Journal article
The effect of high-altitude on human skeletal muscle energetics: P-MRS results from the Caudwell Xtreme Everest expedition.
- Abstract:
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Many disease states are associated with regional or systemic hypoxia. The study of healthy individuals exposed to high-altitude hypoxia offers a way to explore hypoxic adaptation without the confounding effects of disease and therapeutic interventions. Using (31)P magnetic resonance spectroscopy and imaging, we investigated skeletal muscle energetics and morphology after exposure to hypobaric hypoxia in seven altitude-naive subjects (trekkers) and seven experienced climbers. The trekkers asce...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 246.9KB)
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- Publisher copy:
- 10.1371/journal.pone.0010681
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Authors
Funding
+ Defence Advanced Research Projects Agency
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Funding agency for:
Edwards, L
Grant:
ASRJMT1
+ Defence Advanced Research Projects Agency
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Funding agency for:
Holloway, C
Grant:
ASRJMT1
Defence Advanced Research Projects Agency
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Medical Research Council
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Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PloS one Journal website
- Volume:
- 5
- Issue:
- 5
- Article number:
- e10681
- Publication date:
- 2010-01-01
- DOI:
- EISSN:
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1932-6203
- ISSN:
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1932-6203
- Source identifiers:
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105262
Item Description
- Language:
- English
- Keywords:
- UUID:
-
uuid:d255062f-abf1-4240-ad89-93a240cfd267
- Local pid:
- pubs:105262
- Deposit date:
- 2012-12-19
Terms of use
- Copyright holder:
- Edwards et al
- Copyright date:
- 2010
- Notes:
- Copyright 2010 Edwards et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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