- Abstract:
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Many disease states are associated with regional or systemic hypoxia. The study of healthy individuals exposed to high-altitude hypoxia offers a way to explore hypoxic adaptation without the confounding effects of disease and therapeutic interventions. Using (31)P magnetic resonance spectroscopy and imaging, we investigated skeletal muscle energetics and morphology after exposure to hypobaric hypoxia in seven altitude-naive subjects (trekkers) and seven experienced climbers. The trekkers asce...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
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(pdf, 246.9KB)
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- Publisher copy:
- 10.1371/journal.pone.0010681
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- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PloS one Journal website
- Volume:
- 5
- Issue:
- 5
- Pages:
- Article: e10681
- Publication date:
- 2010-01-01
- DOI:
- EISSN:
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1932-6203
- ISSN:
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1932-6203
- URN:
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uuid:d255062f-abf1-4240-ad89-93a240cfd267
- Source identifiers:
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105262
- Local pid:
- pubs:105262
- Copyright holder:
- Edwards et al.
- Copyright date:
- 2010
- Notes:
- Copyright 2010 Edwards et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Journal article
The effect of high-altitude on human skeletal muscle energetics: P-MRS results from the Caudwell Xtreme Everest expedition.
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Defence Advanced Research Projects Agency
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Medical Research Council
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