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MicroRNA miR-107 is overexpressed in pituitary adenomas and inhibits the expression of aryl hydrocarbon receptor-interacting protein in vitro.

Abstract:

Abnormal microRNA (miRNA) expression profiles have recently been associated with sporadic pituitary adenomas, suggesting that miRNAs can contribute to tumor formation; miRNAs are small noncoding RNAs that inhibit posttranscriptional expression of target mRNAs by binding to target sequences usually located in the 3'-UTR. In this study, we investigated the role played by miR-107, a miRNA associated with different human cancers, in sporadic pituitary adenomas and its interaction with the pituita...

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Publication status:
Published

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Publisher copy:
10.1152/ajpendo.00546.2011

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Journal:
American journal of physiology. Endocrinology and metabolism More from this journal
Volume:
303
Issue:
6
Pages:
E708-E719
Publication date:
2012-09-01
DOI:
EISSN:
1522-1555
ISSN:
0193-1849

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