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Journal article

Contribution of innate immune cells to pathogenesis of severe influenza virus infection.

Abstract:

Influenza A viruses (IAVs) cause respiratory illness of varying severity based on the virus strains, host predisposition and pre-existing immunity. Ultimately, outcome and recovery from infection rely on an effective immune response comprising both innate and adaptive components. The innate immune response provides the first line of defence and is crucial to the outcome of infection. Airway epithelial cells are the first cell type to encounter the virus in the lungs, providing antiviral and c...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1042/CS20160484

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Department:
Oxford, MSD, NDM, NDM Experimental Medicine
Role:
Author

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Publisher:
Portland Press Publisher's website
Journal:
Clinical Science Journal website
Volume:
131
Issue:
4
Pages:
269-283
Publication date:
2017-01-05
DOI:
ISSN:
0143-5221 and 1470-8736
Pubs id:
pubs:673401
URN:
uri:d1a73f6c-8b08-4e1a-b104-e7a455cff66e
UUID:
uuid:d1a73f6c-8b08-4e1a-b104-e7a455cff66e
Local pid:
pubs:673401
Language:
English
Keywords:

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