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Endogenous triglyceride-rich lipoproteins accumulate in rat plasma when competing with a chylomicron-like triglyceride emulsion for a common lipolytic pathway.

Abstract:

The rat liver secretes very low density lipoproteins (VLDL) containing either apoB-100 or apoB-48. After oral fat intake, chylomicrons containing apoB-48 and endogenously synthesized VLDL are mixed in the blood and the triglyceride clearance from these triglyceride-rich lipoprotein species compete for the same lipolytic pathway, i.e., lipoprotein lipase. A situation mimicking alimentary lipemia was induced by a short-term intravenous primed infusion of a chylomicron-like triglyceride emulsion...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM, Biomedical Research Centre
Journal:
Journal of lipid research
Volume:
36
Issue:
7
Pages:
1557-1566
Publication date:
1995-07-05
ISSN:
0022-2275
URN:
uuid:d1a5aa08-2e43-4f72-92ce-b9ab2577d74d
Source identifiers:
18404
Local pid:
pubs:18404

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