Cessation of daily wheel running differentially alters fat oxidation capacity in liver, muscle, and adipose tissue.
Physical inactivity is associated with the increased risk of developing chronic metabolic diseases. To understand early alterations caused by physical inactivity, we utilize an animal model in which rats are transitioned from daily voluntary wheel running to a sedentary condition. In the hours and days following this transition, adipose tissue mass rapidly increases, due in part to increased lipogenesis. However, whether a concurrent decrease in fatty acid oxidative capacity (FAO) in skeletal...Expand abstract
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- Journal of applied physiology (Bethesda, Md. : 1985)
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