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Cessation of daily wheel running differentially alters fat oxidation capacity in liver, muscle, and adipose tissue.

Abstract:

Physical inactivity is associated with the increased risk of developing chronic metabolic diseases. To understand early alterations caused by physical inactivity, we utilize an animal model in which rats are transitioned from daily voluntary wheel running to a sedentary condition. In the hours and days following this transition, adipose tissue mass rapidly increases, due in part to increased lipogenesis. However, whether a concurrent decrease in fatty acid oxidative capacity (FAO) in skeletal...

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Authors


Rector, RS More by this author
Borengasser, SJ More by this author
Naples, SP More by this author
Uptergrove, GM More by this author
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Journal:
Journal of applied physiology (Bethesda, Md. : 1985)
Volume:
106
Issue:
1
Pages:
161-168
Publication date:
2009-01-05
DOI:
EISSN:
1522-1601
ISSN:
8750-7587
URN:
uuid:d1984a19-4cf5-4b92-b69e-0f0517245c17
Source identifiers:
110335
Local pid:
pubs:110335

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