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Lipocortin 1 (annexin 1): a candidate paracrine agent localized in pituitary folliculo-stellate cells.

Abstract:

It is now well established that lipocortin 1 (LC1) plays an important role as a mediator of early delayed glucocorticoid feedback action in the hypothalamo-hypophysial system. In both the hypothalamus and anterior pituitary gland, LC1 mimics some of the actions of glucocorticoids; moreover, glucocorticoids stimulate the synthesis of LC1 and cause the translocation of intracellular LC1 to the outer cell surface. The mechanism by which LC1 acts in these tissues is only partially understood, but...

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Publication status:
Published

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Publisher copy:
10.1210/en.140.9.4311

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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
Journal:
Endocrinology
Volume:
140
Issue:
9
Pages:
4311-4319
Publication date:
1999-09-01
DOI:
EISSN:
1945-7170
ISSN:
0013-7227
Source identifiers:
113639
Language:
English
Keywords:
Pubs id:
pubs:113639
UUID:
uuid:d17931eb-4b50-423a-8f15-adef5fab85f0
Local pid:
pubs:113639
Deposit date:
2012-12-19

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