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Endochondral ossification in vitro is influenced by mechanical bending.

Abstract:

Bone development is influenced by the local mechanical environment. Experimental evidence suggests that altered loading can change cell proliferation and differentiation in chondro- and osteogenesis during endochondral ossification. This study investigated the effects of three-point bending of murine fetal metatarsal bone anlagen in vitro on cartilage differentiation, matrix mineralization and bone collar formation. This is of special interest because endochondral ossification is also an impo...

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Publication status:
Published

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Publisher copy:
10.1016/j.bone.2006.10.011

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Institution:
University of Oxford
Department:
Oxford, MPLS, Engineering Science
Role:
Author
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Journal:
Bone
Volume:
40
Issue:
3
Pages:
597-603
Publication date:
2007-03-05
DOI:
EISSN:
1873-2763
ISSN:
8756-3282
URN:
uuid:d0e39212-016b-48e8-918c-cd5aef7478bf
Source identifiers:
428222
Local pid:
pubs:428222

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