Bone development is influenced by the local mechanical environment. Experimental evidence suggests that altered loading can change cell proliferation and differentiation in chondro- and osteogenesis during endochondral ossification. This study investigated the effects of three-point bending of murine fetal metatarsal bone anlagen in vitro on cartilage differentiation, matrix mineralization and bone collar formation. This is of special interest because endochondral ossification is also an impo...Expand abstract
- Publication status:
- Publisher copy:
- Copyright date:
Endochondral ossification in vitro is influenced by mechanical bending.
Views and Downloads
If you are the owner of this record, you can report an update to it here: Report update to this record