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Mechanisms associated with the trajectory of depressive and anxiety symptoms: A linear mixed-effects model during the COVID-19 Pandemic

Abstract:
The present study investigates differences in the trajectories of anxiety, depression, and sleep problems among infected versus non-infected case-controlled individuals. Patients who tested positive for COVID-19 were selected from a representative sample in Norway (N > 10,000). In total, 126 of these individuals were infected during the project period, and this group was analyzed at T5 (May 2021). Of these positive cases, those who had completed both PHQ-9 and GAD-7 at all three measurement points were selected for longitudinal analysis using multilevel modeling. There was a significant difference at T5 between those who had tested positive for COVID-19 and matched controls. Anxiety and depression were reduced among those who tested positive, but there were no differences in trajectory when compared to matched controls. Limitations include the use of self-report measures and the assessment of symptoms at a time when strict virus mitigation protocols were in place. The present findings indicate that individuals who test positive for COVID-19 exhibit higher levels of depressive symptoms after restrictions are lifted. However, comparison of anxiety and depression symptom trajectories with matched controls reveals that both groups exhibited stable or slightly decreased symptoms.publishedVersio
Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Role:
Author
ORCID:
0000-0002-8335-2217
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Role:
Author
ORCID:
0000-0002-8042-8570
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Role:
Author
ORCID:
0000-0001-7190-4187


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Funder identifier:
10.13039/501100005366


Publisher:
Springer
Journal:
Current Psychology More from this journal
Volume:
42
Issue:
34
Pages:
30696-30713
Publication date:
2022-02-04
DOI:
EISSN:
1936-4733
ISSN:
1046-1310


Language:
English
Keywords:
Pubs id:
1995519
Local pid:
pubs:1995519
Source identifiers:
W4225276631
Deposit date:
2026-06-11
ARK identifier:
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